MUCOADHESIVE IN SITU RECTAL GEL LOADED WITH RIFAMPICIN: STRATEGY TO IMPROVE BIOAVAILABILITY AND ALLEVIATE LIVER TOXICITY

Mucoadhesive In Situ Rectal Gel Loaded with Rifampicin: Strategy to Improve Bioavailability and Alleviate Liver Toxicity

Although it is a front-line in tuberculosis treatment, rifampicin (RF) exhibits poor oral bioavailability and hepatotoxicity.Rectal mucoadhesive and in situ rectal gels were developed to overcome drug drawbacks.A RF/polyethylene glycol 6000 co-precipitate was first prepared in different ratios.Based on the drug solubility, the selected ratio was in

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Overhead transmission line condition assessment based on intention classification and slot filling using optimized BERT model

As the key equipment in power system, the running SCOOP state of overhead transmission lines is affected by various complex and random factors, and the maintenance workload of the line is too heavy to overhaul regularly.Therefore, it is very necessary to build a refined condition assessment system to improve the diagnosis accuracy and maintenance e

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Decolorization of Textile Dyes by Extracellular Enzymes Produced from Trametes sanguinea and Perenniporia taephropora Immobilized on Natural Media

The color of textile wastewater is still a main problem in wastewater treatment by biological processes.The colored effluents from textile factories usually exceed effluent standards.Therefore, various innovations were developed to treat textile wastewater for decolorization in the effluents.This research aims to decolorize textile wastewater by im

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